4-1BBL/TNFSF9 Monoklonaler Antikörper

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• KD/KO Validated

4-1BBL/TNFSF9 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

4

CloneNo.

1B4B1

Kat-Nr. : 66450-1-Ig

Synonyme

4 1BB L, 4 1BB ligand, 4 1BBL, CD137L, TNFSF9

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Galerie der Validierungsdaten

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  WB analysis of Raji using 66450-1-Ig

  Raji, Ramos, Daudi, and K-562 cells were subjected to SDS PAGE followed by western blot with 66450-1-Ig (TNFSF9 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Raji-Zellen, Daudi-Zellen, K-562-Zellen, Ramos-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 2 publications below
• WB: See 3 publications below
• IHC: See 2 publications below
• IF: See 1 publications below

Produktinformation

66450-1-Ig bindet in WB, IHC, IF, ELISA 4-1BBL/TNFSF9 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: 4-1BBL/TNFSF9 fusion protein Ag12768
• Vollständiger Name: tumor necrosis factor (ligand) superfamily, member 9
• Berechnetes Molekulargewicht: 254 aa, 27 kDa
• Beobachtetes Molekulargewicht: 27 kDa
• GenBank-Zugangsnummer: BC104805
• Gene symbol: TNFSF9
• Gene ID (NCBI): 8744
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TNFSF9, also named as 4-1BBL, belongs to the tumor necrosis factor family. It is a cytokine that binds to TNFRSF9. TNSF9 induces the proliferation of activated peripheral blood T-cells. It may have a role in activation-induced cell death (AICD) and may play a role in cognate interactions between T-cells and B-cells/macrophages.

Publikationen

Species	Application	Title
human	WB,IHC	Aging (Albany NY); TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.; Authors - Jiao Wu ; KD Validated
human	WB,IF	Int Immunopharmacol; TNFSF9 promotes metastasis of pancreatic cancer by regulating M2 polarization of macrophages through Src/FAK/p-Akt/IL-1β signaling; Authors - Jiao Wu ; KD Validated
human	IHC	BMC Cancer; Clinical significance of nonerythrocytic spectrin Beta 1 (SPTBN1) in human kidney renal clear cell carcinoma and uveal melanoma: a study based on Pan-Cancer Analysis; Authors - Wenting Tang
human	WB	Hepatol Commun; HBV infection effects prognosis and activates the immune response in intrahepatic cholangiocarcinoma; Authors - Zhizhen Li