TCR beta Monoklonaler Antikörper

TCR beta Monoklonal Antikörper für FC

Wirt / Isotyp

Armenian Hamster / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

H57-597

Kat-Nr. : 65106-1-Ig

Synonyme

T cell receptor beta chain, Tcrb, Tib

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Galerie der Validierungsdaten

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  FC experiment of mouse splenocytes using 65106-1-Ig

  1X10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse TCR beta (65106-1-Ig, Clone:H57-597) and FITC Goat anti-hamster (Armenian) IgG Antibody at dilution 1:200 (green), or stained with 0.5 ug isotype control antibody and FITC Goat anti-hamster (Armenian) IgG Antibody at dilution 1:200 (black). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65106-1-Ig bindet in FC TCR beta und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Armenian Hamster / IgG
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Affinitätsgereinigtes TCR aus Maus-DO-11.10-Zellen
• Vollständiger Name: T-cell receptor beta chain
• Gene symbol: Tcrb
• Gene ID (NCBI): 21577
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: Phosphatbasierter Puffer mit 0,09% Natriumazid, pH 7,2.
• Lagerungsbedingungen: Bei 2-8℃ lagern.

Hintergrundinformationen

T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).