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  • KD/KO Validated

STOML2 Monoklonaler Antikörper

STOML2 Monoklonal Antikörper für IHC, IP, WB, ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, IP, IHC, IF, ELISA

Konjugation

Unkonjugiert

CloneNo.

1A2E9

Kat-Nr. : 60052-1-Ig

Synonyme

EPB72 like protein 2, HSPC108, SLP 2, SLP2, stomatin (EPB72) like 2, Stomatin like protein 2, STOML2



Geprüfte Anwendungen

Erfolgreiche Detektion in WBHausschwein-Hirngewebe, HepG2-Zellen, MCF-7-Zellen, RAW 264.7-Zellen
Erfolgreiche IPMaushirngewebe
Erfolgreiche Detektion in IHChumanes Magenkrebsgewebe, humanes Endometriumkarzinomgewebe
Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:5000-1:20000
Immunpräzipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunhistochemie (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

60052-1-Ig bindet in WB, IP, IHC, IF, ELISA STOML2 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, Maus
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen STOML2 fusion protein Ag0363
Vollständiger Name stomatin (EPB72)-like 2
Berechnetes Molekulargewicht 356 aa, 39 kDa
Beobachtetes Molekulargewicht 39 kDa
GenBank-ZugangsnummerBC002442
Gene symbol STOML2
Gene ID (NCBI) 30968
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Human stomatin (band 7.2b) is a 31-kDa erythrocyte membrane protein of unknown function but implicated in the control of ion channel permeability, mechanoreception, and lipid domain organization. Stomatin (EPB72)-like 2 (STOML2, synonyms: SLP-2, HSPC108) is a 38.5-kDa protein that is overall approximately 20% similar to human stomatin. STOML2 is also present in mature human erythrocytes , but lacks a characteristic NH(2)-terminal hydrophobic domain found in other stomatin homologues. STOML2 may link stomatin or other integral membrane proteins to the peripheral cytoskeleton and thereby play a role in regulating ion channel conductances or the organization of sphingolipid and cholesterol-rich lipid rafts.

Protokolle

Produktspezifische Protokolle
WB protocol for STOML2 antibody 60052-1-IgProtokoll herunterladen
IHC protocol for STOML2 antibody 60052-1-IgProtokoll herunterladen
IP protocol for STOML2 antibody 60052-1-IgProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
humanWB

Science

Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division.

Authors - Shun Nagashima
  • KD Validated
humanWB

Mol Cell Proteomics

An informatics-assisted label-free approach for personalized tissue membrane proteomics: case study on colorectal cancer.

Authors - Han Chia-Li CL
human,mouseIF,IP

Int J Mol Sci

The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.

Authors - Meiyu Cheng
humanIHC

Int J Cancer

Novel prognostic protein markers of resectable pancreatic cancer identified by coupled shotgun and targeted proteomics using formalin-fixed paraffin-embedded tissues.

Authors - Takadate Tatsuyuki T
humanWB

Cell Death Dis

Stomatin-like protein 2 regulates survivin expression in non-small cell lung cancer cells through β-catenin signaling pathway.

Authors - Cheng-Ta Yang
  • KD Validated
humanWB

J Cell Sci

Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes.

Authors - Chongshu Jian
  • KD Validated