SCRN1 Polyklonaler Antikörper

SCRN1 Polyklonal Antikörper für WB,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, CoIP, ELISA

Konjugation

Unkonjugiert

Publikationen

3

Kat-Nr. : 14303-1-AP

Synonyme

KIAA0193, SCRN1, secernin 1, SES1

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Galerie der Validierungsdaten

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  WB analysis of A549 using 14303-1-AP

  A549 cells were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of A549 using 14303-1-AP

  A549 cells were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse brain using 14303-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse brain using 14303-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HeLa using 14303-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: A549-Zellen, HeLa-Zellen, Maushirngewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 2 publications below
• CoIP: See 1 publications below

Produktinformation

14303-1-AP bindet in WB, CoIP, ELISA SCRN1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SCRN1 fusion protein Ag5413
• Vollständiger Name: secernin 1
• Berechnetes Molekulargewicht: 46 kDa
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC040492
• Gene symbol: SCRN1
• Gene ID (NCBI): 9805
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SCRN genes encode protein members of the secernin family including Secernin 1, Secernin 2 and Secernin 3. Function of Secernin 2 and Secernin 3 are so far not well understood. Secernin 1 is a novel 50-kDa cytosolic protein that appears to be involved in the regulation of exocytosis from peritoneal mast cells. Secernin-1 a novel tumor-associated antigen (TAA) and may be a universal marker of different cancer types including gastric cancer, which has been validated by several researches. Measurement of SCRN1 can be used in the early detection of cancer or in the surveillance of patients who undergo surgery.

Publikationen

Species	Application	Title
mouse	WB	Front Mol Neurosci; Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice; Authors - Xiaoxia Li
mouse	WB	Biochem Biophys Res Commun; Proteomic profiling of brain cortex tissues in a Tau transgenic mouse model of Alzheimer's disease.; Authors - Seong-Hun Chang
human	CoIP	J Mol Cell Biol; ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis; Authors - Xueyao Ma