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  • KD/KO Validated

RND3 Monoklonaler Antikörper

RND3 Monoklonal Antikörper für WB,ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

Hausschwein, human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

3H8F9

Kat-Nr. : 66228-1-Ig

Synonyme

ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3



Geprüfte Anwendungen

Erfolgreiche Detektion in WBfetales humanes Hirngewebe

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

KD/KOSee 1 publications below
WBSee 3 publications below

Produktinformation

66228-1-Ig bindet in WB, ELISA RND3 und zeigt Reaktivität mit Hausschwein, human

Getestete Reaktivität Hausschwein, human
In Publikationen genannte Reaktivitäthuman
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen RND3 fusion protein Ag18839
Vollständiger Name Rho family GTPase 3
Berechnetes Molekulargewicht 244 aa, 27 kDa
Beobachtetes Molekulargewicht 29 kDa
GenBank-ZugangsnummerBC012513
Gene symbol RND3
Gene ID (NCBI) 390
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.

Protokolle

Produktspezifische Protokolle
WB protocol for RND3 antibody 66228-1-IgProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
humanWB

Mol Ther Nucleic Acids

Downregulated lncRNA HOXA11-AS Affects Trophoblast Cell Proliferation and Migration by Regulating RND3 and HOXA7 Expression in PE.

Authors - Yetao Xu
humanWB

Int J Mol Med

Ingenuity pathway analysis of differentially expressed genes involved in signaling pathways and molecular networks in RhoE gene‑edited cardiomyocytes.

Authors - Zhongming Shao
  • KO Validated
humanWB

Virology

Transcriptomic analysis reveals crucial regulatory roles of immediate-early response genes and related signaling pathways in coronavirus infectious bronchitis virus infection

Authors - Li Xia Yuan

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Yuan (Verified Customer) (12-10-2020)

This antibody is very good quality and can detect RND3 in both U937 and PBMC cells.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:1000
  • Cell Tissue Type: U937 & PBMC