PI3 Kinase p55 Gamma Polyklonaler Antikörper

PI3 Kinase p55 Gamma Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen

6

Kat-Nr. : 55036-1-AP

Synonyme

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Galerie der Validierungsdaten

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Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 6 publications below

Produktinformation

55036-1-AP bindet in WB, ELISA PI3 Kinase p55 Gamma und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
• Berechnetes Molekulargewicht: 54 kDa
• GenBank-Zugangsnummer: NM_003629
• Gene symbol: PIK3R3
• Gene ID (NCBI): 8503
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20℃ lagern. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PIK3R3, also named as p55PIK, belongs to the PI3K p85 subunit family. It binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During INS stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The antibody is specific to PIK3R3.

Publikationen

Species	Application	Title
mouse	WB	RNA Biol; MicroRNA-432 targeting E2F3 and P55PIK inhibits myogenesis through PI3K/AKT/mTOR signaling pathway.; Authors - Meilin Ma
human	WB	Mol Biol Cell; MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway.; Authors - Xu Lin L
human	WB	Tumour Biol; MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3.; Authors - Gang Cao
rat	WB	Transl Androl Urol; Study on the mechanism of aging-related erectile dysfunction based on bioinformatics and experimental verification; Authors - Taotao Sun
human	WB	Tumour Biol; Upregulation of HOXB7 promotes the tumorigenesis and progression of gastric cancer and correlates with clinical characteristics.; Authors - Jia-Qin Cai
rat	WB	Andrology; Saxagliptin alleviates erectile dysfunction through increasing SDF-1 in diabetes mellitus; Authors - Taotao Sun