NeutraControl HGF Monoklonaler Antikörper

NeutraControl HGF Monoklonal Antikörper für Non-Neutralization, ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

Non-Neutralization, ELISA

Konjugation

Unkonjugiert

CloneNo.

2G4G8

Kat-Nr. : 69527-1-Ig

Synonyme

F TCF, Hepatocyte growth factor, Hepatopoeitin A, HGF, HGFB, HPTA, Scatter factor, SF



Produktinformation

69527-1-Ig bindet in Non-Neutralization, ELISA HGF und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen human Humankine HGF protein HZ-1084
Vollständiger Name hepatocyte growth factor (hepapoietin A; scatter factor)
Gene symbol HGF
Gene ID (NCBI) 3082
Konjugation Unkonjugiert
Form Lyophilized Powder
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer Sterile PBS.
Endotoxin<0.1 EU/μg
WiederherstellungThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Hintergrundinformationen

Hepatocyte growth factor (HGF) is the most potent mitogen of mature hepatocytes in primary culture. HGF is derived from a biologically inactive single chain precursor of 728 amino acids (pro-HGF) localized mostly on the cell surface and in the extracellular matrix. The mature form produced following proteolytic cleavage is composed of a 69-kDa α-subunit (containing four kringle domains) and the 34 kDa β-subunit, similar to the catalytic domain of serine proteases, but with amino acid substitutions in the active site. HGF is a pleiotropic cytokine which exerts a variety of effects on several cells, being involved in the regulation of many biological processes, such as inflammation, tissue repair, morphogenesis, angiogenesis, tumour propagation, immunomodulation of viral infections and cardio-metabolic activities.

This antibody is a neutralizing control antibody for HGF, the immunogen is the same as Neutrakine 69027-1-Ig but could not neutralize human HGF.