NR2E3 Monoklonaler Antikörper

NR2E3 Monoklonal Antikörper für WB,ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, Maus

Anwendung

WB,ELISA

Konjugation

Unkonjugiert

CloneNo.

1G1D9

Kat-Nr. : 66494-1-Ig

Synonyme

ESCS, NR2E3, PNR, rd7, RNR, RP37

---

Galerie der Validierungsdaten

• 

  WB analysis of pig retina using 66494-1-Ig

  pig retina tissue were subjected to SDS PAGE followed by western blot with 66494-1-Ig (NR2E3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse retina using 66494-1-Ig

  mouse retina tissue were subjected to SDS PAGE followed by western blot with 66494-1-Ig (NR2E3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Hausschwein-Retina-Gewebe, Maus-Retina-Gewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

66494-1-Ig bindet in WB,ELISA NR2E3 und zeigt Reaktivität mit Hausschwein, Maus

• Getestete Reaktivität: Hausschwein, Maus
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: NR2E3 fusion protein Ag5831
• Vollständiger Name: nuclear receptor subfamily 2, group E, member 3
• Berechnetes Molekulargewicht: 45 kDa
• Beobachtetes Molekulargewicht: 45-50 kDa
• GenBank-Zugangsnummer: BC041421
• Gene symbol: NR2E3
• Gene ID (NCBI): 10002
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]