NCOR2 Polyklonaler Antikörper

NCOR2 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF, CoIP, ELISA

Konjugation

Unkonjugiert

Publikationen

3

Kat-Nr. : 20017-1-AP

Synonyme

CTG repeat protein 26, CTG26, N CoR2, NCOR2, Nuclear receptor corepressor 2, SMAP270, SMRT, SMRTE, SMRTE tau, T3 receptor associating factor, TNRC14, TRAC, TRAC 1, TRAC1

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Galerie der Validierungsdaten

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  WB analysis of HeLa using 20017-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 20017-1-AP (NCOR2 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours.

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  WB analysis of Jurkat using 20017-1-AP

  Jurkat cells were subjected to SDS PAGE followed by western blot with 20017-1-AP (NCOR2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IF: See 1 publications below
• CoIP: See 1 publications below

Produktinformation

20017-1-AP bindet in WB, IF, CoIP, ELISA NCOR2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: nuclear receptor co-repressor 2
• Berechnetes Molekulargewicht: 275 kDa
• Beobachtetes Molekulargewicht: 180 kDa
• GenBank-Zugangsnummer: NM_006312
• Gene symbol: NCOR2
• Gene ID (NCBI): 9612
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NCOR2, also named as CTG26, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC-1, TRAC1 and SMAP270, belongs to the N-CoR nuclear receptor corepressors family. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. The antibody recognizes all the isoforms of NCOR2. An about 180 KDa was also reported(PMID: 23081895).

Publikationen

Species	Application	Title
human	CoIP	Adv Sci (Weinh); Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.; Authors - Shaliu Luo
human	WB	Cancer Sci; LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells.; Authors - Yangjun Wu
	IF	Front Pharmacol; Analysis of Effect of Schisandra in the Treatment of Myocardial Infarction Based on Three-Mode Gene Ontology Network.; Authors - Siyao Hu