CXCL9/MIG Polyklonaler Antikörper

CXCL9/MIG Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (1)

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen

7

Rezensionen (1)

Kat-Nr. : 22355-1-AP

Synonyme

C X C motif chemokine 9, CMK, crg 10, CXCL9, Humig, MIG, MIG; CXCL9, SCYB9, Small inducible cytokine B9

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Galerie der Validierungsdaten

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  WB analysis using 22355-1-AP

  IFN gamma and LPS treated THP-1 cells were subjected to SDS PAGE followed by western blot with 22355-1-AP (CXCL9/MIG antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 2 publications below
• IHC: See 6 publications below

Produktinformation

22355-1-AP bindet in WB, IHC, ELISA CXCL9/MIG und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CXCL9/MIG fusion protein Ag17932
• Vollständiger Name: chemokine (C-X-C motif) ligand 9
• Berechnetes Molekulargewicht: 14 kDa
• Beobachtetes Molekulargewicht: 14 kDa
• GenBank-Zugangsnummer: BC095396
• Gene symbol: CXCL9
• Gene ID (NCBI): 4283
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CXCL9 is a small cytokine known as MIG. CXCL9 is a T-cell chemoattractant, which is induced by IFN-γ. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. A high level of CXCL9 revealed in peripheral liquids, can be considered as a marker of host immune response, especially of that involving Th1 cells.

Publikationen

Species	Application	Title
human,mouse	IHC	Front Immunol; LRPPRC facilitates tumor progression and immune evasion through upregulation of m6A modification of PD-L1 mRNA in hepatocellular carcinoma; Authors - Houhong Wang
human	IHC	Front Immunol; Avoiding Absolute Quantification Trap: A Novel Predictive Signature of Clinical Benefit to Anti-PD-1 Immunotherapy in Non-Small Cell Lung Cancer.; Authors - Chengming Liu
human	IHC	Cancer Cell Int; Activation of the chemokine receptor 3 pathway leads to a better response to immune checkpoint inhibitors in patients with metastatic urothelial carcinoma.; Authors - Wenqin Feng
human	IHC	Biomedicines; Identification and Preliminary Clinical Validation of Key Extracellular Proteins as the Potential Biomarkers in Hashimoto's Thyroiditis by Comprehensive Analysis; Authors - Zihan Xi
human	IHC	J Plast Surg Hand Surg; A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.; Authors - Xinhang Dong
human,mouse	WB	Mol Ther; Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8+ T cell activity; Authors - Xiaojin Luan

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

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FH

Wojciech (Verified Customer) (05-25-2023)

This antibody works well. It was used for IHC analysis of mouse meningeal tissue at dilution of 1:200. Blocking in 0.3% Triton-X-100 containing 2% of goat serum for 1 hour.

• Applications: Immunohistochemistry
• Primary Antibody Dilution: 1:200
• Cell Tissue Type: mouse meninges