Ly-6G/Ly-6C (Gr-1) Monoklonaler Antikörper

Ly-6G/Ly-6C (Gr-1) Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2b, kappa

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Atlantic Blue™ Fluorescent Dye

CloneNo.

RB6-8C5

Kat-Nr. : AB-65140

Synonyme

Gr1, Gr-1, Ly 6G, Ly6g, Ly-6G (Gr-1)



Geprüfte Anwendungen

Erfolgreiche Detektion in FCMaus-Knochenmarkzellen

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

AB-65140 bindet in FC Ly-6G/Ly-6C (Gr-1) und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Ratte / IgG2b, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Gegen Granulozyten murinen Ursprungs gezüchtet
Vollständiger Name lymphocyte antigen 6 complex, locus G
GenBank-ZugangsnummerX70920
Gene symbol Ly6g
Gene ID (NCBI) 546644
Konjugation Atlantic Blue™ Fluorescent Dye
Excitation/Emission maxima wavelengths404 nm / 458 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Ly-6G (lymphocyte antigen 6 complex, locus G), also known as Gr-1, is a 21-25 kDa, glycosylphosphatidylinositol-anchored protein expressed on myeloid lineage cells in mouse bone marrow (PMID: 8360469). The expression of Ly-6G increases on neutrophils as they differentiate from immature cells in the bone marrow to mature cells in the blood and spleen (PMID: 8890901). Antibodies targeting Ly6G (RB6-8C5 or 1A8) are commonly used in studies aimed at identifying the role of neutrophils (PMID: 23543767). The RB6-8C5 mAb has been reported to cross-react with Ly-6C on cells expressing Ly-6C (PMID: 8360469).

Protokolle

Produktspezifische Protokolle
FC protocol for Atlantic Blue™ Ly-6G/Ly-6C (Gr-1) antibody AB-65140Protokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen