LZIC Polyklonaler Antikörper

LZIC Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14543-1-AP

Synonyme

LZIC, Protein LZIC

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Galerie der Validierungsdaten

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  WB analysis of BxPC-3 using 14543-1-AP

  BxPC-3 cells were subjected to SDS PAGE followed by western blot with 14543-1-AP (LZIC antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of BxPC-3 using 14543-1-AP

  BxPC-3 cells were subjected to SDS PAGE followed by western blot with 14543-1-AP (LZIC antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HepG2 using 14543-1-AP

  HepG2 cells were subjected to SDS PAGE followed by western blot with 14543-1-AP (LZIC antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HEK-293 using 14543-1-AP

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 14543-1-AP (LZIC antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: BxPC-3-Zellen, HEK-293-Zellen, HepG2-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

14543-1-AP bindet in WB, ELISA LZIC und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LZIC fusion protein Ag6047
• Vollständiger Name: leucine zipper and CTNNBIP1 domain containing
• Berechnetes Molekulargewicht: 21 kDa
• Beobachtetes Molekulargewicht: 21-24 kDa
• GenBank-Zugangsnummer: BC063443
• Gene symbol: LZIC
• Gene ID (NCBI): 84328
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

LZIC is closely related to ICAT, a physiological inhibitor of the Wnt pathway that interacts physically and functionally with β-catenin to prevent the transcription of Wnt target genes. LZIC's ICAT-homologous region is highly similar to ICAT with particular conservation of residues that are used by ICAT for β-catenin-binding. LZIC does not interact with β-catenin in vitro or in vivo. LZIC is a protein conserved in vertebrates, is required for neuronal survival.