KLRG1 Monoklonaler Antikörper

KLRG1 Monoklonal Antikörper für FC

Wirt / Isotyp

Golden Syrian Hamster / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

2F1

Kat-Nr. : CL488-65084

Synonyme

2F1 Ag, Klrg1, MAFA, MAFA L

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Galerie der Validierungsdaten

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  FC experiment of mouse splenocytes using CL488-65084

  1X10^6 mouse splenocytes were surface stained with APC Anti-Mouse NK1.1 (CD161) (APC-65138, Clone: PK136) and 5 ul CoraLite® Plus 488 Anti-Mouse KLRG1 (CL488-65084, Clone: 2F1). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using CL488-65084

  1X10^6 mouse splenocytes were surface stained with APC Anti-Mouse NK1.1 (CD161) (APC-65138, Clone: PK136) and CoraLite® Plus 488 conjugated Hamster IgG isotype control. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

CL488-65084 bindet in FC KLRG1 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Golden Syrian Hamster / IgG
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: killer cell lectin-like receptor subfamily G, member 1
• GenBank-Zugangsnummer: BC101953
• Gene symbol: Klrg1
• Gene ID (NCBI): 50928
• Konjugation: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS mit 0,1% Natriumazid und 0,5% BSA, pH 7,3.
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).