IL-1F7/IL-37 Monoklonaler Antikörper

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• KD/KO Validated

IL-1F7/IL-37 Monoklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human und mehr (1)

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen

7

CloneNo.

7F1A1

Kat-Nr. : 60296-1-Ig

Synonyme

FIL1, FIL1 zeta, FIL1(ZETA), FIL1Z, IL 1 zeta, IL 1F7, IL 1H4, IL 1RP1, IL 1X, IL1F7, IL-1F7, IL1H4, IL1RP1, IL37, IL-37, Interleukin 1 family member 7, Interleukin 1 homolog 4, Interleukin 1 related protein, Interleukin 1 zeta

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Galerie der Validierungsdaten

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  IHC staining of human colon using 60296-1-Ig

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 60296-1-Ig (IL37 antibody at dilution of 1:200 (under 10x lens).

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  IHC staining of human colon using 60296-1-Ig

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 60296-1-Ig (IL37 antibody at dilution of 1:200 (under 40x lens).

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  IHC staining of human breast cancer using 60296-1-Ig

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 60296-1-Ig (IL37 antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human breast cancer using 60296-1-Ig

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 60296-1-Ig (IL37 antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Kolongewebe, humanes Mammakarzinomgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 6 publications below
• IHC: See 2 publications below

Produktinformation

60296-1-Ig bindet in WB, IHC, ELISA IL-1F7/IL-37 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: IL-1F7/IL-37 fusion protein Ag2441
• Vollständiger Name: interleukin 1 family, member 7 (zeta)
• Berechnetes Molekulargewicht: 218 aa, 24 kDa
• GenBank-Zugangsnummer: BC020637
• Gene symbol: IL1F7
• Gene ID (NCBI): 27178
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Publikationen

Species	Application	Title
human	WB	Cell Mol Immunol; Common genetic heterogeneity of human interleukin-37 leads to functional variance.; Authors - Jingjing Yan
human	WB	Sci Rep; Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinoma.; Authors - Lin Lin
human	WB,IHC	Lab Invest; IL-37bΔ1-45 suppresses the migration and invasion of endometrial cancer cells by targeting the Rac1/NF-κB/MMP2 signal pathway.; Authors - Xishuang Wang ; KD Validated
human	WB	Cell Death Dis; IL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway.; Authors - Chang Jia
mouse	IHC	JCI Insight; Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis; Authors - Nan Ma
human	WB	Sci Immunol; Myeloid cell-derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement; Authors - Graeme P Sullivan