HVCN1 Monoklonaler Antikörper

HVCN1 Monoklonal Antikörper für IF

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

IF

Konjugation

CoraLite®594 Fluorescent Dye

CloneNo.

1E4C4

Kat-Nr. : CL594-66449

Synonyme

HV1, HVCN1, VSOP

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Galerie der Validierungsdaten

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  IF Staining of human tonsillitis using CL594-66449

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 HVCN1 antibody (CL594-66449, Clone: 1E4C4 ) at dilution of 1:200.

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  IF Staining of human tonsillitis using CL594-66449

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 HVCN1 antibody (CL594-66449, Clone: 1E4C4 ) at dilution of 1:200.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IF: humanes Tonsillitisgewebe

Empfohlene Verdünnung

• Immunfluoreszenz (IF): IF : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

CL594-66449 bindet in IF HVCN1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: HVCN1 fusion protein Ag5350
• Vollständiger Name: hydrogen voltage-gated channel 1
• Berechnetes Molekulargewicht: 273 aa, 32 kDa
• Beobachtetes Molekulargewicht: 28-35 kDa, 40 kDa, 60 kDa
• GenBank-Zugangsnummer: BC032672
• Gene symbol: HVCN1
• Gene ID (NCBI): 84329
• Konjugation: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: BS mit 50% Glyzerin, 0,05% Proclin300, 0,5% BSA, pH 7,3.
• Lagerungsbedingungen: Bei -20°C lagern. Vor Licht schützen. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

HVCN1, also named as VSOP and HV1, Belongs to the hydrogen channel family. HVCN1 mediates the voltage-dependent proton permeability of excitable membranes. It forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, HVCN1 is accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. HVCN1, the voltage-sensitive proton channel, is present in human sperm and is an important regulator of the functional maturation of sperm. HVCN1 has four isoforms with MW 28-32 kDa or 40 kDa (modification). It has a dimer form with MW 60 kDa.