Hemopexin Polyklonaler Antikörper

Hemopexin Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

4

Kat-Nr. : 15736-1-AP

Synonyme

Beta 1B glycoprotein, hemopexin, HPX

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Galerie der Validierungsdaten

• 

  WB analysis of human plasma using 15736-1-AP

  human blood were subjected to SDS PAGE followed by western blot with 15736-1-AP (Hemopexin antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse serum using 15736-1-AP

  mouse serum were subjected to SDS PAGE followed by western blot with 15736-1-AP (Hemopexin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Blutgewebe, mouse serum, human plasma

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 2 publications below
• IHC: See 1 publications below
• IF: See 1 publications below

Produktinformation

15736-1-AP bindet in WB, IHC, IF, ELISA Hemopexin und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Hemopexin fusion protein Ag8533
• Vollständiger Name: hemopexin
• Berechnetes Molekulargewicht: 254 aa, 29 kDa
• Beobachtetes Molekulargewicht: 65-75 kDa
• GenBank-Zugangsnummer: BC005395
• Gene symbol: HPX
• Gene ID (NCBI): 3263
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Hemopexin (HPX) is the plasma protein responsible for scavenging heme, thus preventing heme-mediated oxidative stress and heme-bound iron loss. In addition, hemopexin blocks heme activation of immune receptors and vascular inflammatory processes. It is mainly expressed in liver, the synthesis of which is induced after inflammation. Alterations of plasma hemopexin level have been linked to disorders like atherosclerosis and inflammatory diseases.

Publikationen

Species	Application	Title
human	WB	Br J Cancer; Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.; Authors - Yanxia Jin
rat	IHC	J Cell Biochem; Differential protein expression profiling by iTRAQ-2D-LC-MS/MS of rats treated with oxaliplatin.; Authors - Xianjun Sun
human	WB	Placenta; SWATH proteomics analysis of placental tissue with intrahepatic cholestasis of pregnancy; Authors - Yuxuan Jiang
mouse	IF	Elife; Myoglobin-derived iron causes wound enlargement and impaired regeneration in pressure injuries of muscle; Authors - Nurul Jannah Mohamed Nasir