FIZ1 Polyklonaler Antikörper

FIZ1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23257-1-AP

Synonyme

FIZ1

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Galerie der Validierungsdaten

• 

  WB analysis of Jurkat using 23257-1-AP

  Jurkat cells were subjected to SDS PAGE followed by western blot with 23257-1-AP (FIZ1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of NIH/3T3 using 23257-1-AP

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 23257-1-AP (FIZ1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HEK-293 using 23257-1-AP

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 23257-1-AP (FIZ1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Jurkat-Zellen, HEK-293-Zellen, NIH/3T3-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

23257-1-AP bindet in WB, ELISA FIZ1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: FIZ1 fusion protein Ag19760
• Vollständiger Name: FLT3-interacting zinc finger 1
• Berechnetes Molekulargewicht: 496 aa, 52 kDa
• Beobachtetes Molekulargewicht: 52 kDa
• GenBank-Zugangsnummer: BC136512
• Gene symbol: FIZ1
• Gene ID (NCBI): 84922
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FLT3 interacting zinc finger 1 (FIZ1) is a ubiquitous expressed protein that composes of 11 C2H2 zinc finger domains spread over the entire protein in clusters of two, three, or four fingers. The interaction of FIZ1 was mapped to the catalytic domain of FLT3, which is a receptor tyrosine kinase involved in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors (10409713). In the mammalian retina, FIZ1 interacts with NRL (Neural-Retina Leucine-zipper), an essential transcriptional activator of rod photoreceptor-specific genes, and the concentration of FIZ1 in the retina will increase during photoreceptor terminal maturation (18854042).