EGFL7 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

EGFL7 Polyklonal Antikörper für IHC,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (2)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

12

Kat-Nr. : 19291-1-AP

Synonyme

EGF like domain, multiple 7, EGF like protein 7, EGFL7, MEGF7, NOTCH4 like protein, RP11 251M1.2, Vascular endothelial statin, VE STATIN, ZNEU1

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Galerie der Validierungsdaten

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  IHC staining of human kidney using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human kidney using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human endometrial cancer using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human breast cancer using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human breast cancer using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human ovary tumor using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human ovary tumor using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human endometrial cancer using 19291-1-AP

  Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue slide using 19291-1-AP (EGFL7 Antibody) at dilution of 1:50 (under 10x lens).

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Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 2 publications below
• WB: See 11 publications below
• IHC: See 4 publications below
• IF: See 1 publications below

Produktinformation

19291-1-AP bindet in WB, IHC, IF, ELISA EGFL7 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: EGFL7 fusion protein Ag6559
• Vollständiger Name: EGF-like-domain, multiple 7
• Berechnetes Molekulargewicht: 273 aa, 30 kDa
• GenBank-Zugangsnummer: BC012377
• Gene symbol: EGFL7
• Gene ID (NCBI): 51162
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Epidermal growth factor-like domain-containing protein 7 (EGFL7), also known as vascular endothelial statin, is an endothelial cell-derived secreted factor that regulates vascular tube formation. This protein may be involved in the growth and proliferation of tumor cells. Recent studies have reported elevated expression of EGFL7 in several tumors and cancer cell lines, including kidney tumors, malignant gliomas, hepatocellular carcinomas, and colon cancers.

Publikationen

Species	Application	Title
human	WB	Blood Adv; The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models.; Authors - Yousef Salama ; KD Validated
human	WB	Mol Ther Nucleic Acids; Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay.; Authors - Chunqing Yang
human	WB,IHC,IF	Front Oncol; Novel Expression of EGFL7 in Osteosarcoma and Sensitivity to Cisplatin.; Authors - Qing Liu
mouse,rat	WB	Sci China Life Sci; Role of EGFL7/EGFR-signaling pathway in migration and invasion of growth hormone-producing pituitary adenomas.; Authors - Qian Liu
human	WB	Hum Gene Ther; Attenuation of EGFL7 expression inhibits growth hormone-producing pituitary adenomas growth and invasion.; Authors - Qian Liu
human	WB,IHC	Tumour Biol; EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway.; Authors - Jianpeng Wang