Cannabinoid receptor 1 Polyklonaler Antikörper

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• KD/KO Validated

Cannabinoid receptor 1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen

1

Kat-Nr. : 29708-1-AP

Synonyme

CANN6, Cannabinoid receptor 1, cannabinoid receptor 1 (brain), CB R, CB1, CB1A, CB1K5, CB1R, CNR, CNR1

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Galerie der Validierungsdaten

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  WB analysis using 29708-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 29708-1-AP (Cannabinoid receptor 1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 29708-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 29708-1-AP (Cannabinoid receptor 1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 29708-1-AP

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 29708-1-AP (Cannabinoid receptor 1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maushirngewebe, Rattenhirngewebe, SH-SY5Y-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 1 publications below

Produktinformation

29708-1-AP bindet in WB, ELISA Cannabinoid receptor 1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Cannabinoid receptor 1 fusion protein Ag31838
• Vollständiger Name: cannabinoid receptor 1 (brain)
• Berechnetes Molekulargewicht: 472 aa, 53 kDa
• Beobachtetes Molekulargewicht: 48 kDa, 66 kDa
• GenBank-Zugangsnummer: BC074812
• Gene symbol: CNR1
• Gene ID (NCBI): 1268
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cannabinoid receptor 1 (CNR1, or CB1) and CNR2 (CB2) are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family. The CB1 receptor is expressed mainly in the brain. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.

Publikationen

Species	Application	Title
mouse	WB	ACS Chem Neurosci; Basolateral Amygdala Cannabinoid CB1 Receptor Controls Formation and Elimination of Social Fear Memory; Authors - Ming Li ; KO Validated