CD86 Monoklonaler Antikörper

CD86 Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

Ratte

Anwendung

FC

Konjugation

CoraLite®594 Fluorescent Dye

CloneNo.

24F

Kat-Nr. : CL594-65224

Synonyme

B7 2, Cd86, CD86 molecule



Geprüfte Anwendungen

Erfolgreiche Detektion in FCLPS-stimulated rat splenocytes

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL594-65224 bindet in FC CD86 und zeigt Reaktivität mit Ratten

Getestete Reaktivität Ratte
Wirt / Isotyp Maus / IgG1, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen HTLV-1-transformed Lewis-S1 rat T cell line
Vollständiger Name CD86 molecule
Berechnetes Molekulargewicht 36 kDa
GenBank-ZugangsnummerNM_020081
Gene symbol Cd86
Gene ID (NCBI) 56822
Konjugation CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response.

Protokolle

Produktspezifische Protokolle
FC protocol for CL594 CD86 antibody CL594-65224Protokoll herunterladen
Standard-Protokolle
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