CD45R (B220) Monoklonaler Antikörper

CD45R (B220) Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a, kappa

Getestete Reaktivität

human, Maus

Anwendung

FC

Konjugation

CoraLite®594 Fluorescent Dye

CloneNo.

RA3-6B2

Kat-Nr. : CL594-65139

Synonyme

B220, Cd45, CD45R, loc, Ly 5, Lyt 4, Ptprc, T200



Geprüfte Anwendungen

Erfolgreiche Detektion in FCMaus-Splenozyten

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL594-65139 bindet in FC CD45R (B220) und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Ratte / IgG2a, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Murines Abelson-Leukämie-virusinduzierte Vorläufer-B-Tumorzellen
Vollständiger Name protein tyrosine phosphatase, receptor type, C
GenBank-ZugangsnummerBC028512
Gene symbol Ptprc
Gene ID (NCBI) 19264
Konjugation CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45R (B220) is an isoform of CD45, expressed on murine B-lineage cells (except for plasma cells) and on a small sub-population of T cells (PMID: 6975314; 15712182). It is commonly used as a pan B-cell marker in mice. CD45R is also expressed on activated T cells and NK cell subsets (PMID: 7514808; 17923504). The RA3-6B2 clone reacts with human and mouse CD45R.

Protokolle

Produktspezifische Protokolle
FC protocol for CL594 CD45R (B220) antibody CL594-65139Protokoll herunterladen
Standard-Protokolle
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