CD45R (B220) Monoklonaler Antikörper
CD45R (B220) Monoklonal Antikörper für FC
Wirt / Isotyp
Ratte / IgG2a, kappa
Getestete Reaktivität
human, Maus
Anwendung
FC
Konjugation
CoraLite®594 Fluorescent Dye
CloneNo.
RA3-6B2
Kat-Nr. : CL594-65139
Synonyme
Galerie der Validierungsdaten
Geprüfte Anwendungen
Erfolgreiche Detektion in FC | Maus-Splenozyten |
Empfohlene Verdünnung
Anwendung | Verdünnung |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
CL594-65139 bindet in FC CD45R (B220) und zeigt Reaktivität mit human, Maus
Getestete Reaktivität | human, Maus |
Wirt / Isotyp | Ratte / IgG2a, kappa |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Murines Abelson-Leukämie-virusinduzierte Vorläufer-B-Tumorzellen |
Vollständiger Name | protein tyrosine phosphatase, receptor type, C |
GenBank-Zugangsnummer | BC028512 |
Gene symbol | Ptprc |
Gene ID (NCBI) | 19264 |
Konjugation | CoraLite®594 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
Form | Liquid |
Reinigungsmethode | Affinitätsreinigung |
Lagerungspuffer | PBS with 0.09% sodium azide. |
Lagerungsbedingungen | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Hintergrundinformationen
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45R (B220) is an isoform of CD45, expressed on murine B-lineage cells (except for plasma cells) and on a small sub-population of T cells (PMID: 6975314; 15712182). It is commonly used as a pan B-cell marker in mice. CD45R is also expressed on activated T cells and NK cell subsets (PMID: 7514808; 17923504). The RA3-6B2 clone reacts with human and mouse CD45R.
Protokolle
Produktspezifische Protokolle | |
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FC protocol for CL594 CD45R (B220) antibody CL594-65139 | Protokoll herunterladen |
Standard-Protokolle | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |