CD38 Monoklonaler Antikörper

CD38 Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a, kappa

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

90

Kat-Nr. : CL488-65059

Synonyme

Cd38, CD38 antigen, Cd38 rs1

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Galerie der Validierungsdaten

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  FC experiment of mouse splenocytes using CL488-65059

  1X10^6 C57BL/6 mouse splenocytes were surface stained with APC Anti-Mouse CD3ε (APC-65060, Clone: 145-2C11) and 1 ug CoraLite® Plus 488-conjugated Anti-Mouse CD38 (CL488-65059, Clone: 90). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using CL488-65059

  1X10^6 C57BL/6 mouse splenocytes were surface stained with APC Anti-Mouse CD3ε (APC-65060, Clone: 145-2C11) and CoraLite® Plus 488-conjugated Rat IgG2a isotype control antibody. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL488-65059 bindet in FC CD38 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG2a, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Maus-Knochenmark-Vorläufer-B-Zellen
• Vollständiger Name: CD38 antigen
• GenBank-Zugangsnummer: BC046312
• Gene symbol: Cd38
• Gene ID (NCBI): 12494
• Konjugation: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS mit 0,1% Natriumazid und 0,5% BSA, pH 7,3.
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).