CD36 Monoklonaler Antikörper

CD36 Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgM, kappa

Getestete Reaktivität

human

Anwendung

FC

Konjugation

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

SMΦ

Kat-Nr. : CL488-65248

Synonyme

CD36, CHDS7, FAT, Fatty acid translocase, Glycoprotein IIIb, GP3B, GP4, GPIIIB, GPIV, PAS 4, PAS IV, PASIV, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, SCARB3, Thrombospondin receptor

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Galerie der Validierungsdaten

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  FC experiment of human peripheral blood platelets using CL488-65248

  1X10^6 human peripheral blood platelets were surface stained with 5 ul CoraLite® Plus 488 Anti-Human CD36 (CL488-65248, Clone:SMΦ), or CoraLite® Plus 488 Mouse IgM Isotype Control. Cells were not fixed. CD41a positive cells were gated.

• 

  FC experiment of human peripheral blood platelets using CL488-65248

  1X10^6 human peripheral blood platelets were surface stained with 5 ul CoraLite® Plus 488 Anti-Human CD36 (CL488-65248, Clone:SMΦ), or CoraLite® Plus 488 Mouse IgM Isotype Control. Cells were not fixed. CD41a positive cells were gated.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human peripheral blood platelets

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

CL488-65248 bindet in FC CD36 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgM, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: CD36 molecule (thrombospondin receptor)
• Berechnetes Molekulargewicht: 472 aa, 53 kDa
• GenBank-Zugangsnummer: BC008406
• Gene symbol: CD36
• Gene ID (NCBI): 948
• Konjugation: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA.
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD36, also named as GP3B and GP4, is an 88-kDa membrane glycoprotein present on platelets, monocytes, erythroid precursors, endothelial cells, and several tumor cell lines. CD36 binds to collagen, thrombospondin, anionic phospholipids, long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport and oxidized LDL. CD36 may function as a cell adhesion molecule. It mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutation of CD36 will cause platelet glycoprotein IV deficiency which known as CD36 deficiency. Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7).