CD276 Monoklonaler Antikörper

CD276 Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG1

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

MJ18

Kat-Nr. : 65221-1-Ig

Synonyme

6030411F23Rik, AU016588, B7h3, B7RP 2, Cd276, CD276 antigen

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Galerie der Validierungsdaten

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  FC experiment of mouse peritoneal macrophages using 65221-1-Ig

  1X10^6 mouse peritoneal macrophages were surface stained with 1 ug Anti-Mouse CD276 (65221-1-Ig, Clone:MJ18) and FITC anti-rat IgG1 Antibody at dilution 1:100 (red), or unstained (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: peritoneale Makrophagen der Maus

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65221-1-Ig bindet in FC CD276 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Mouse IgG2a Fc-CD276 (aa 1-242) fusion protein
• Vollständiger Name: CD276 antigen
• GenBank-Zugangsnummer: BC019436
• Gene symbol: Cd276
• Gene ID (NCBI): 102657
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide.
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD276 (also known as B7-H3) is a type I transmembrane protein expressed on many tissues and cell types. CD276 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, CD276 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).