CD14 Monoklonaler Antikörper

CD14 Monoklonal Antikörper für FC, ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

FC, ELISA

Konjugation

Unkonjugiert

CloneNo.

26IC

Kat-Nr. : 65246-1-Ig

Synonyme

CD14, CD14 molecule

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Galerie der Validierungsdaten

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  FC experiment of human PBMCs using 65246-1-Ig

  1X10^6 human PBMCs were surface stained with 0.2 ug Anti-Human CD14 (65246-1-Ig, Clone:26IC) and APC-conjugated Goat Anti-Mouse IgG at dilution 1:1000 (red) or unstained. Cells were not fixed. Monocytes were gated.

• 

  FC experiment of human PBMCs using 65246-1-Ig

  1X10^6 human PBMCs were surface stained with 0.2 ug Anti-Human CD14 (65246-1-Ig, Clone:26IC) and APC-conjugated Goat Anti-Mouse IgG at dilution 1:1000 or unstained. Cells were not fixed. Monocytes were gated.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65246-1-Ig bindet in FC, ELISA CD14 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: CD14 molecule
• Berechnetes Molekulargewicht: 375 aa, 40 kDa
• GenBank-Zugangsnummer: BC010507
• Gene symbol: CD14
• Gene ID (NCBI): 929
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide.
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD14 is a 50-55 kDa glycosylphosphatidylinositol-anchored glycoprotein preferentially expressed on monocytes and macrophages, and at lower levels on granulocytes (PMID: 3385210; 2462937; 7685797). CD14 can also exist as a soluble protein. CD14 acts as a co-receptor for bacterial liposaccharides (LPS) (PMID: 1698311). It plays a major role in the inflammatory response of monocytes to LPS.