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CD11c/Integrin Alpha X Monoklonaler Antikörper

CD11c/Integrin Alpha X Monoklonal Antikörper für IF

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

IF

Konjugation

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

2F1C10

Kat-Nr. : CL488-60258

Synonyme

CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6

Galerie der Validierungsdaten

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  • Immunofluorescence (IF) / fluorescent staining of human tonsillitis tissue using CoraLite® Plus 488-conjugated CD11c/Integrin Alpha (CL488-60258)

    IF Staining of human tonsillitis using CL488-60258

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite® Plus 488 CD11c/Integrin Alpha X antibody (CL488-60258, Clone: 2F1C10 ) at dilution of 1:200.

  • Immunofluorescence (IF) / fluorescent staining of human tonsillitis tissue using CoraLite® Plus 488-conjugated CD11c/Integrin Alpha (CL488-60258)

    IF Staining of human tonsillitis using CL488-60258

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite® Plus 488 CD11c/Integrin Alpha X antibody (CL488-60258, Clone: 2F1C10 ) at dilution of 1:200.

Geprüfte Anwendungen

Erfolgreiche Detektion in IFhumanes Tonsillitisgewebe

Empfohlene Verdünnung

AnwendungVerdünnung
Immunfluoreszenz (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

IFSee 1 publications below

Produktinformation

CL488-60258 bindet in IF CD11c/Integrin Alpha X und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen CD11c/Integrin Alpha X fusion protein Ag11350
Vollständiger Name integrin, alpha X (complement component 3 receptor 4 subunit)
Berechnetes Molekulargewicht 1169 aa, 129 kDa
GenBank-ZugangsnummerBC038237
Gene symbol ITGAX
Gene ID (NCBI) 3687
Konjugation CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer BS mit 50% Glyzerin, 0,05% Proclin300, 0,5% BSA, pH 7,3.
LagerungsbedingungenBei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a 145-150 kDa type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis. And this anitbody is CL488(Ex/Em 488 nm/515 nm) conjugated.

Protokolle

Produktspezifische Protokolle
IF protocol for CL Plus 488 CD11c/Integrin Alpha X antibody CL488-60258Protokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouseIF

Clin Cancer Res

18F-FMISO PET Imaging Identifies Hypoxia and Immunosuppressive Tumor Microenvironments and Guides Targeted Evofosfamide Therapy in Tumors Refractory to PD-1 and CTLA-4 Inhibition.

Authors - Kirsten M Reeves
View Article