CD11c Monoklonaler Antikörper

CD11c Monoklonal Antikörper für FC

Wirt / Isotyp

Armenian Hamster / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

CoraLite®594 Fluorescent Dye

CloneNo.

N418

Kat-Nr. : CL594-65130

Synonyme

AI449405, Cd11c, Cr4, integrin alpha X, Itgax, N418



Geprüfte Anwendungen

Erfolgreiche Detektion in FCMaus-Splenozyten

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL594-65130 bindet in FC CD11c und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Armenian Hamster / IgG
Klonalität Monoklonal
Typ Antikörper
Immunogen Dendritische Mausmilzzellen
Vollständiger Name integrin alpha X
GenBank-ZugangsnummerBC167225
Gene symbol Itgax
Gene ID (NCBI) 16411
Konjugation CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS mit 0,1% Natriumazid und 0,5% BSA, pH 7,3.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).

Protokolle

Produktspezifische Protokolle
FC protocol for CL594 CD11c antibody CL594-65130Protokoll herunterladen
Standard-Protokolle
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