CD11b Monoklonaler Antikörper

CD11b Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgG2a, kappa

Getestete Reaktivität

Ratte

Anwendung

FC

Konjugation

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

OX42

Kat-Nr. : CL488-65229

Synonyme

Cd11b, integrin alpha M, Itgam



Geprüfte Anwendungen

Erfolgreiche Detektion in FCRatten-Splenozyten

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CL488-65229 bindet in FC CD11b und zeigt Reaktivität mit Ratten

Getestete Reaktivität Ratte
Wirt / Isotyp Maus / IgG2a, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Rat peritoneal macrophages
Vollständiger Name integrin alpha M
Berechnetes Molekulargewicht127 kDa
GenBank-ZugangsnummerNM_012711
Gene symbol Itgam
Gene ID (NCBI) 25021
Konjugation CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

Protokolle

Produktspezifische Protokolle
FC protocol for CL Plus 488 CD11b antibody CL488-65229Protokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen