CD11a Monoklonaler Antikörper

CD11a Monoklonal Antikörper für

Wirt / Isotyp

Maus / Mouse IgG1, kappa

Getestete Reaktivität

human

Anwendung

Konjugation

CoraLite® Plus 594 Fluorescent Dye

CloneNo.

TS2/4

Kat-Nr. : CL594-65194

Synonyme

CD11A, Integrin alpha L, ITGAL, LFA 1, LFA 1A, LFA1A



Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is N/A per 10^6 cells in a 100 µl suspension or N/A per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

CL594-65194 bindet in CD11a und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / Mouse IgG1, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen HLA-DR CTL-Linie
Vollständiger Name integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Berechnetes Molekulargewicht 129 kDa
GenBank-ZugangsnummerBC008777
Gene symbol ITGAL
Gene ID (NCBI) 3683
Konjugation CoraLite® Plus 594 Fluorescent Dye
Excitation/Emission maxima wavelengths593 nm / 614 nm
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS mit 0,1% Natriumazid und 0,5% BSA, pH 7,3.
LagerungsbedingungenBei 2-8°C lagern. Vor Licht schützen.

Hintergrundinformationen

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).