CD11a Monoklonaler Antikörper
CD11a Monoklonal Antikörper für
Wirt / Isotyp
Maus / Mouse IgG1, kappa
Getestete Reaktivität
human
Anwendung
Konjugation
CoraLite® Plus 594 Fluorescent Dye
CloneNo.
TS2/4
Kat-Nr. : CL594-65194
Synonyme
Galerie der Validierungsdaten
Geprüfte Anwendungen
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is N/A per 10^6 cells in a 100 µl suspension or N/A per 100 µl of whole blood. | |
| Sample-dependent, check data in validation data gallery | |
Produktinformation
CL594-65194 bindet in CD11a und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / Mouse IgG1, kappa |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | HLA-DR CTL-Linie |
| Vollständiger Name | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| Berechnetes Molekulargewicht | 129 kDa |
| GenBank-Zugangsnummer | BC008777 |
| Gene symbol | ITGAL |
| Gene ID (NCBI) | 3683 |
| Konjugation | CoraLite® Plus 594 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 593 nm / 614 nm |
| Form | Liquid |
| Reinigungsmethode | Protein-G-Reinigung |
| Lagerungspuffer | PBS mit 0,1% Natriumazid und 0,5% BSA, pH 7,3. |
| Lagerungsbedingungen | Bei 2-8°C lagern. Vor Licht schützen. |
Hintergrundinformationen
CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).
