CD11a Monoklonaler Antikörper

CD11a Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a, kappa

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

M17/4

Kat-Nr. : 65177-1-Ig

Synonyme

Cd11a, integrin alpha L, Itgal, LFA 1, Ly 15, Ly 21

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Galerie der Validierungsdaten

• 

  FC experiment of mouse thymocytes using 65177-1-Ig

  1X10^6 mouse thymocytes were surface stained with 0.5 ug Anti-Mouse CD11a (65177-1-Ig, Clone:M17/4) (red), or 0.5 ug Isotype Control. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Thymozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65177-1-Ig bindet in FC CD11a und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG2a, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: C57BL/6 Mausmilz sekundäre cytotoxische T-Zellen
• Vollständiger Name: integrin alpha L
• GenBank-Zugangsnummer: BC145802
• Gene symbol: Itgal
• Gene ID (NCBI): 16408
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Mit Protein-A-Affinitätschromatographie gereinigt
• Lagerungspuffer: PBS with 0.09% sodium azide.
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).