BAMBI Polyklonaler Antikörper

BAMBI Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC,ELISA

Konjugation

Unkonjugiert

Publikationen

7

Kat-Nr. : 16100-1-AP

Synonyme

BAMBI, Non metastatic gene A protein

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Galerie der Validierungsdaten

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Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 7 publications below
• IHC: See 1 publications below

Produktinformation

16100-1-AP bindet in WB, IHC,ELISA BAMBI und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: BAMBI fusion protein Ag8974
• Vollständiger Name: BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
• Berechnetes Molekulargewicht: 260 aa, 29 kDa
• GenBank-Zugangsnummer: BC019252
• Gene symbol: BAMBI
• Gene ID (NCBI): 25805
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BAMBI (BMP and activin membrane-bound inhibitor homolog) is a transmembrane protein and modulator of paracrine factors that regulate adipogenesis, including transforming growth factor (TGF) superfamily members (TGF-β and BMP) and Wnt. BAMBI is a type I TGFβ receptor antagonist and contributes to endothelial and vascular homeostasis. BAMBI deregulation has been involved in the pathogenesis of various human pathologies, such as tumor progression andmetastatic capability, pathological fibrosis and metaplastic bone formation.

Publikationen

Species	Application	Title
human	WB,IHC	J Cell Mol Med; Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis.; Authors - Li Sun
mouse	WB	Sci Rep; The roles of Toll-like receptor 4 in the pathogenesis of pathogen-associated biliary fibrosis caused by Clonorchis sinensis.; Authors - Chao Yan
rat	WB	Toxicology; Chlorogenic acid reduces liver inflammation and fibrosis through inhibition of toll-like receptor 4 signaling pathway.; Authors - Shi Haitao H
mouse	WB	PLoS One; Effect of miR-20b on Apoptosis, Differentiation, the BMP Signaling Pathway and Mitochondrial Function in the P19 Cell Model of Cardiac Differentiation In Vitro.; Authors - Shasha Zhu
human	WB	J Dermatol; miR-205-5p inhibits psoriasis-associated proliferation and angiogenesis: Wnt/β-catenin and mitogen-activated protein kinase signaling pathway are involved.; Authors - Yadong Xue
human	WB	J Cancer; Exosomal miR-17-5p promotes angiogenesis in nasopharyngeal carcinoma via targeting BAMBI.; Authors - Bingyue Duan