STAT6 antibody (pAb)
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
WB
Cat No : 61547,61548 61547
Synonyms
Validation Data Gallery
Product Information
Tested Applications |
WB
Applications Validated by Active Motif: WB: 1:1,000 - 1:2,000 dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required. |
Tested Reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | This antibody was raised against a peptide within the C-terminal region of human STAT6. This antibody detects two isoforms of STAT6. |
Full Name | STAT6 antibody (pAb) |
Synonyms | STAT6, Signal Transducer And Activator Of Transcription 6 Interleukin-4 Induced, STAT Interleukin4-Induced, Transcription Factor IL-4 STAT, IL-4-STAT, IL-4 Stat, STAT6B, STAT6C, Signal Transducer And Activator Of Transcription 6, signal transduction, transcription activation, western blotting, wb, polyclonal, pab, antibody, sample |
Molecular weight | 100 & 85 kDa |
GenBank accession number | NP_003144 |
RRID | AB_2793675 |
Purification Method | Affinity Purified |
Buffer | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
Storage | Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage. |
Background Information
STAT6 (signal transducer and activator of transcription 6) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT6 plays a central role in exerting IL4 mediated biological responses.