Recombinant CTBP1 protein
Expressed In
E. coli
Protein Species
Human
Cat No : 81250
Validation Data Gallery
Product Information
| Expressed In | E. coli |
| Protein Species | Human |
Contents
Recombinant CTBP1 protein is supplied in 25 mM Tris-HCl pH 8.0, 500 mM NaCl, 10% glycerol, 0.5 mM TCEP.
Background
CTBP1 (C-Terminal Binding Protein 1), also written as CtBP1, is a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. It’s a corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. It also has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Application Notes
This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for this product is shown.
Protein Details
Recombinant CTBP1 protein was expressed in E.coli as the full length protein (accession number (NP_001319.1) with an N-terminal 6x-His Tag. The molecular weight of the protein is 51.1 kDa.
Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Guarantee
This product is guaranteed for 6 months from date of receipt.
This product is for research use only and is not for use in diagnostic procedures.