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NRF1 antibody (pAb)

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse

Applications

WB

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Cat No : 61673,61674 61673

Synonyms

NRF1, Nuclear Respiratory Factor 1, Alpha Palindromic-Binding Protein, NRF-1, ALPHA-PAL, Alpha-pal, transcription, transcriptional activator, activator EIF2-alpha, respiration, heme biosynthesis, mitochondrial DNA transcription, antibody, antibodies, polyclonal, pab, western blotting, wb, sample

Validation Data Gallery

  • NRF1 antibody (pAb) tested by Western blot. Nuclear extract (30 ug) of C2C12 (Lane 1) and HepG2 cells (Lane 2) probed with NRF1 antibody at a 1:500 dilution.

    NRF1 antibody (pAb) tested by Western blot. Nuclear extract (30 ug) of C2C12 (Lane 1) and HepG2 cells (Lane 2) probed with NRF1 antibody at a 1:500 dilution.

Product Information

Tested Applications WB

Applications Validated by Active Motif: WB: 1:500 - 1:1,500 dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.
Tested Reactivity Human, Mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen This antibody was raised against a peptide within the C-terminal region of human NRF1.
Full Name NRF1 antibody (pAb)
Synonyms NRF1, Nuclear Respiratory Factor 1, Alpha Palindromic-Binding Protein, NRF-1, ALPHA-PAL, Alpha-pal, transcription, transcriptional activator, activator EIF2-alpha, respiration, heme biosynthesis, mitochondrial DNA transcription, antibody, antibodies, polyclonal, pab, western blotting, wb, sample
Molecular weight 68 kDa
GenBank accession numberNP_001280092
RRIDAB_2793729
Purification Method Affinity Purified
Buffer Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Storage Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Background Information

NRF1 (Nuclear Respiratory Factor 1) is a transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.