MRG15 antibody (pAb)
Host / Isotype
Rabbit / IgG
Reactivity
Human, Wide Range Predicted
Applications
WB
Cat No : 39361,39362 39361
Synonyms
Validation Data Gallery
Product Information
| Tested Applications |
WB
Applications Validated by Active Motif: WB: 1:250 - 1:1,000 dilution |
| Tested Reactivity | Human, Wide Range Predicted |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | This MRG15 antibody was raised against a peptide corresponding to the C-terminus of human MRG15. |
| Full Name | MRG15 antibody (pAb) |
| Synonyms | hEaf3, MORF4L1, MORFRG15, NuA4, MORF-related gene, Eaf3, chromodomain, pAb, polyclonal, MORF4-Related Gene on chromosome 15, antibody, antibodies, sample |
| Molecular weight | 39 kDa |
| GenBank accession number | NP_996670 |
| RRID | AB_2615022 |
| Purification Method | Affinity Purified |
| Buffer | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| Storage | Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage. |
Background Information
MRG15 (MORF4-Related Gene on chromosome 15) is the homolog of the yeast Eaf3 protein and belongs to the MRG family of genes, which are involved in various cellular processes as cellular aging, positive and negative transcriptional regulation and DNA damage repair. MRG15 can be associated with both histone deacetylase and histone acetyltransferase complexes (such as the NuA4 histone acetyltransferase complex, which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal Histone H2A and Histone H4). MRG15, thus, potentially plays a role in both transcriptional silencing and activation. In addition to the more conserved MRG motifs, MRG15 also contains a chromodomain near the N-terminus.