MAZ antibody (mAb) (Clone 133)

Host / Isotype

Mouse / IgG

Reactivity

Human

Applications

ChIP, EMSA, WB

CloneNo.

133

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Cat No : 39935,39936 39935

Synonyms

Maz, Myc-associated zinc finger protein, transcription factor, c-Myc promoter, ME1a1, ME1a2, Sp, skeletal muscle development, PPAR-gamma, sample, dbdabs



Product Information

Tested Applications ChIP, EMSA, WB

Applications Validated by Active Motif: WB This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91205.

Tested Reactivity Human
Host / Isotype Mouse / IgG
Class Monoclonal
Type Antibody
Immunogen This MAZ antibody was raised against recombinant human MAZ protein.
Full Name MAZ antibody (mAb) (Clone 133)
Synonyms Maz, Myc-associated zinc finger protein, transcription factor, c-Myc promoter, ME1a1, ME1a2, Sp, skeletal muscle development, PPAR-gamma, sample, dbdabs
Molecular weight 55 kDa
GenBank accession numberNP_002374
RRIDAB_2793398
Purification Method Protein G Chromatography
Buffer Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Storage Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Background Information

MAZ (Myc-associated zinc finger protein) functions as a transcription factor roles in both transcription initiation and termination. MAZ binds to two sites within the c-Myc promoter, ME1a1 and ME1a2. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. MAZ also participates in skeletal muscle development through the activation of several skeletal muscle-specific genes. MAZ has also been reported to drive tumor-specific expression of PPAR-gamma in breast cancer cells.