MAZ antibody (mAb) (Clone 133)
Host / Isotype
Mouse / IgG
Reactivity
Human
Applications
ChIP, EMSA, WB
CloneNo.
133
Cat No : 39935,39936 39935
Synonyms
Validation Data Gallery
Product Information
Tested Applications |
ChIP, EMSA, WB
Applications Validated by Active Motif: WB This antibody is also available as an AbFlex engineered recombinant antibody. For details on the corresponding AbFlex Recombinant Antibody, see Catalog No. 91205. |
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG |
Class | Monoclonal |
Type | Antibody |
Immunogen | This MAZ antibody was raised against recombinant human MAZ protein. |
Full Name | MAZ antibody (mAb) (Clone 133) |
Synonyms | Maz, Myc-associated zinc finger protein, transcription factor, c-Myc promoter, ME1a1, ME1a2, Sp, skeletal muscle development, PPAR-gamma, sample, dbdabs |
Molecular weight | 55 kDa |
GenBank accession number | NP_002374 |
RRID | AB_2793398 |
Purification Method | Protein G Chromatography |
Buffer | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
Storage | Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage. |
Background Information
MAZ (Myc-associated zinc finger protein) functions as a transcription factor roles in both transcription initiation and termination. MAZ binds to two sites within the c-Myc promoter, ME1a1 and ME1a2. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. MAZ also participates in skeletal muscle development through the activation of several skeletal muscle-specific genes. MAZ has also been reported to drive tumor-specific expression of PPAR-gamma in breast cancer cells.