IRF-3 antibody (pAb)

Host / Isotype

Rabbit / Serum

Reactivity

Human

Applications

ChIP, WB

Cat No : 39371,39372

Synonyms

IRF-3, irf-3, irf, IRF, pAb, polyclonal, Interferon Regulatory Factor 3, antibody, antibodies, sample, dbdabs

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Validation Data Gallery

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  IRF-3 pAb tested by Western blot. Detection of IRF-3 by Western blot analysis. The presence of IRF-3 in nuclear extracts derived from U-937 (IFNg) cells is confirmed using IRF-3 rabbit polyclonal antibody at a 1:1,000 dilution.

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Product Information

• Tested Applications: ChIP, WB

  Applications Validated by Active Motif: WB: 1:1,000 - 1:2,000 dilution

• Tested Reactivity: Human
• Host / Isotype: Rabbit / Serum
• Class: Polyclonal
• Type: Antibody
• Immunogen: This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
• Full Name: IRF-3 antibody (pAb)
• Synonyms: IRF-3, irf-3, irf, IRF, pAb, polyclonal, Interferon Regulatory Factor 3, antibody, antibodies, sample, dbdabs
• Molecular weight: 50 kDa
• GenBank accession number: NP_001562
• RRID: AB_2793232
• Purification Method: None
• Buffer: Rabbit serum containing 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
• Storage: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Background Information

IRF-3 (Interferon regulatory factor 3 or IRF3) is a member of the IRF family of transcription factors that include IRF-1, IRF-6 and IRF-7. IRF-3 that has been phosphorylated at serine/threonine forms a complex with CREBBP and translocates to the nucleus to activate transcription of interferon-induced genes.