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FosB antibody (mAb) (Clone 83B1138)

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB

CloneNo.

83B1138

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Cat No : 40960 40960

Synonyms

FosB, Fos-B, Fos B, mAb, monoclonal, FBJ murine osteosarcoma viral oncogene homolog B, antibody, antibodies, dbdabs

Validation Data Gallery

  • FosB mAb tested by Western blot. Detection of FosB by Western blot. The analysis was performed using HeLa nuclear extract and FosB mAb. A protein of approximate MW of 46 kDa was detected. The lower MW protein detected at 34 kDa may be the isoform of D2D FosB.

    FosB mAb tested by Western blot. Detection of FosB by Western blot. The analysis was performed using HeLa nuclear extract and FosB mAb. A protein of approximate MW of 46 kDa was detected. The lower MW protein detected at 34 kDa may be the isoform of D2D FosB.

Product Information

Tested Applications WB

Applications Validated by Active Motif: WB: 1 - 2 ug/ml dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.
Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen This FosB antibody was raised against a peptide corresponding to amino acid residues 2-14 of human FosB.
Full Name FosB antibody (mAb) (Clone 83B1138)
Synonyms FosB, Fos-B, Fos B, mAb, monoclonal, FBJ murine osteosarcoma viral oncogene homolog B, antibody, antibodies, dbdabs
Molecular weight 46 kDa
GenBank accession numberNP_001107643
RRIDAB_2793459
Purification Method Affinity Purified
Buffer PBS containing 0.02% sodium azide. Sodium azide is highly toxic.
Storage Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Background Information

FosB (FBJ murine osteosarcoma viral oncogene homolog B or Fos B) is a member of the Fos gene family of leucine zipper proteins that dimerize with the Jun family of proteins to form transcription factor AP-1. AP-1 controls cellular processes such as differentiation, proliferation and apoptosis. Other AP-1 family members consist of c-Fos, Fra-1, Fra-2, c-Jun, JunB and JunD.