• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

FOXO4 antibody (pAb)

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse

Applications

WB

Activ Motif logo

Cat No : 61573,61574 61573

Synonyms

FOXO4, Forkhead Box O4, Fork Head Domain Transcription Factor AFX1, MLLT7, AFX, AFX1, Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog); Translocated To, 7, Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated To, 7, Forkhead Box Protein O4, polyclonal, pab, antibodies, antibody, western blotting, wb, sample

Validation Data Gallery

  • FOXO4 antibody (pAb) tested by Western blot. Detection of FOXO4 antibody by Western blot analysis. Cytoplasmic extract (20 ug) of mouse testis (lane 1), HeLa (lane 2), and Jurkat (lane 3). All probed with FOXO4 antibody at a dilution of 1:500.

    FOXO4 antibody (pAb) tested by Western blot. Detection of FOXO4 antibody by Western blot analysis. Cytoplasmic extract (20 ug) of mouse testis (lane 1), HeLa (lane 2), and Jurkat (lane 3). All probed with FOXO4 antibody at a dilution of 1:500.

Product Information

Tested Applications WB

Applications Validated by Active Motif: WB: 1:500 - 1:2,000 dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.
Tested Reactivity Human, Mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen This antibody was raised against synthetic peptides containing human FOXO4.
Full Name FOXO4 antibody (pAb)
Synonyms FOXO4, Forkhead Box O4, Fork Head Domain Transcription Factor AFX1, MLLT7, AFX, AFX1, Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog); Translocated To, 7, Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated To, 7, Forkhead Box Protein O4, polyclonal, pab, antibodies, antibody, western blotting, wb, sample
Molecular weight 60 kDa
GenBank accession numberNP_005929
RRIDAB_2793682
Purification Method Affinity Purified
Buffer Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Storage Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Background Information

FOXO4 (Forkhead Box O4) is a transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.