CD18 Monoklonaler Antikörper

CD18 Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a, kappa

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

FITC Fluorescent Dye

CloneNo.

M18/2

Kat-Nr. : FITC-65178

Synonyme

2E6, AI528527, Cd18, integrin beta 2, Itgb2, LAD, LCAMB, Lfa1, MF17

---

Galerie der Validierungsdaten

• 

  FC experiment of mouse splenocytes using FITC-65178

  1X10^6 mouse splenocytes were surface stained with 0.5 ug FITC Anti-Mouse CD18 (FITC-65178, Clone: M18/2) (red), or 0.5 ug Control Antibody. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using FITC-65178

  1X10^6 mouse splenocytes were surface stained with 0.5 ug FITC Anti-Mouse CD18 (FITC-65178, Clone: M18/2) (red), or 0.5 ug Control Antibody. Cells were not fixed.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

FITC-65178 bindet in FC CD18 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG2a, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Maus-CTL-Glykoprotein
• Vollständiger Name: integrin beta 2
• GenBank-Zugangsnummer: BC145644
• Gene symbol: Itgb2
• Gene ID (NCBI): 16414
• Konjugation: FITC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 494 nm / 520 nm
• Form: Liquid
• Reinigungsmethode: Der gereinigte Antikörper ist mit Fluoresceinisothiocyanat (FITC) unter optimalen Bedingungen konjugiert. Das Konjugat wird mit Größenausschluss-Chromatographie gereinigt.
• Lagerungspuffer: PBS mit 0,1% Natriumazid.
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).