SGLT1 Polyclonal antibody
SGLT1 Polyclonal Antibody for WB, IP, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, mouse
Applications
WB, IP, ELISA
Conjugate
Unconjugated
Cat no : 30861-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | mouse colon tissue, mouse kidney tissue |
Positive IP detected in | mouse kidney tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
30861-1-AP targets SGLT1 in WB, IP, ELISA applications and shows reactivity with Human, mouse samples.
Tested Reactivity | Human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | SGLT1 fusion protein Ag29338 |
Full Name | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
Calculated Molecular Weight | 73 kDa |
Observed Molecular Weight | 73 kDa |
GenBank Accession Number | NM_000343 |
Gene Symbol | SLC5A1 |
Gene ID (NCBI) | 6523 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
SLC5A1, also known as SGLT1, is a sodium-dependent glucose transporter (SGLT) family member. SGLT1 couples sugar transport to Na+ gradients across the intestinal brush border (PMID: 8563765). SGLT1 mediates active glucose and galactose absorption in the intestine and renal glucose scavenging. Mutations in SGLT1 cause glucose-galactose malabsorption (GGM) syndrome (PMID: 34880492). SGLT1 is expressed in intestine and endometrial cells (PMID: 2490366, 28974690).
Protocols
Product Specific Protocols | |
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WB protocol for SGLT1 antibody 30861-1-AP | Download protocol |
IP protocol for SGLT1 antibody 30861-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |