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  • KD/KO Validated

GPRIN1 Polyclonal antibody

GPRIN1 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IP, IF, IHC, ELISA

Conjugate

Unconjugated

Cat no : 13771-1-AP

Synonyms

GPRIN1, GRIN1, KIAA1893



Tested Applications

Positive WB detected inmouse brain tissue
Positive IP detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13771-1-AP targets GPRIN1 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GPRIN1 fusion protein Ag4754
Full Name G protein regulated inducer of neurite outgrowth 1
Calculated Molecular Weight 1008 aa, 102 kDa
Observed Molecular Weight 100-110 kDa
GenBank Accession NumberBC052950
Gene Symbol GPRIN1
Gene ID (NCBI) 114787
RRIDAB_2114013
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GPRIN1 (G protein-regulated inducer of neurite outgrowth 1), also named GRIN1, may be involved in neurite outgrowth. Western blotting analysis has confirmed its expression in mouse neuroblastoma and rat pheochromocytoma cells. And both GPRIN1 and GNAO1 are membrane-bound proteins that are enriched in the growth cones of neurites (PMID:10480904). It has 2 isoforms produced by alternative splicing. This antibody detects GRIN1 at bands around 110 kDa.

Protocols

Product Specific Protocols
WB protocol for GPRIN1 antibody 13771-1-APDownload protocol
IP protocol for GPRIN1 antibody 13771-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB,IHC,IF

Sci Signal

Dynamic interactions of the 5-HT6 receptor with protein partners control dendritic tree morphogenesis.

Authors - Camille N Pujol
  • KD Validated
mouseWB

J Biol Chem

DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory.

Authors - Li Yi Y
humanWB

Exp Ther Med

Chronic ethanol exposure induces SK-N-SH cell apoptosis by increasing N-methyl-D-aspartic acid receptor expression and intracellular calcium.

Authors - Hongbo Wang