ERVWE1 Polyclonal antibody

ERVWE1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 23172-1-AP

Synonyms

env, Env W, Envelope polyprotein gPr73, Enverin, ERVW-1, ERVWE1, gp24, gp50 Transmembrane protein, HERV 7q, HERV 7q Envelope protein, HERV W, HERV W ENV, HERV W envelope protein, HERVW, SU, syncytin, Syncytin 1, Syncytin-1, TM

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Validation Data Gallery

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  WB analysis using 23172-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 23172-1-AP (ERVWE1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse testis tissue, rat testis tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

23172-1-AP targets ERVWE1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: ERVWE1 fusion protein Ag19227
• Full Name: endogenous retroviral family W, env(C7), member 1
• Calculated Molecular Weight: 538 aa, 60 kDa
• Observed Molecular Weight: 70-73 kDa
• GenBank Accession Number: BC137381
• Gene Symbol: ERVWE1
• Gene ID (NCBI): 30816
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ERVWE1 encodes a 538 amino-acid, 73-kDa glycosylated (60 kDa unglycosylated) envelope protein, Syncytin-1. It is expressed in the placental syncytiotrophoblast and participates in syncytium formation during placenta morphogenesis. Mounting evidence suggests that aberrant expression of ERVWE1 involves the etiology of schizophrenia.