TIPE2 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 15940-1-AP

Featured Product KD/KO validated

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Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse cerebellum tissue, mouse small intestine tissue, mouse spleen tissue, rat lymph tissue, rat spleen tissue

Positive IP detected in:
mouse cerebellum tissue

Positive IHC detected in:
human lymphoma tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
tumor necrosis factor, alpha-induced protein 8-like 2

Calculated molecular weight:
184aa,21 kDa

Observed molecular weight:
18-21 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

Inflammation factor protein 20, TIPE2, TNFAIP8 like protein 2, TNFAIP8L2

TIPE2 (TNF-α-inducible protein 8-like 2, or TNFAIP8L2), a negative immune regulator, is essential for maintaining immune homeostasis. TIPE2 shares considerable sequence homology with members of the tumor necrosis factor-α-inducible protein 8 (TNFAIP8) family, which are thought to regulate cellular and immune homeostasis. TIPE2 acts as a negative regulator of Toll-like receptor and T-cell receptor function and is preferentially expressed in lymphoid tissues. TIPE2 plays an essential role for a signal transduction pathway that links inflammatory immune response to specific conditions after cerebral ischemia

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