DSE Antibody
Rabbit Polyclonal
Catalog number: 10452-1-AP
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Applications
| Tested applications | ELISA, IHC |
| Cited applications | IF, IHC |
| Species specificity | Human,Mouse,Rat; other species not tested. |
| Cited species | human |
| Positive IHC detected in | human liver cancer |
| Recommended dilution | IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Immunohistochemical of paraffin-embedded human liver cancer using 10452-1-AP(DSE antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human liver cancer using 10452-1-AP(DSE antibody) at dilution of 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | DSE fusion protein ag0695 | Full name | dermatan sulfate epimerase |
|
Calculated molecular weight |
958 aa,110kd |
Observed molecular
weight |
|
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GenBank accession number |
BC039245 | Gene ID (NCBI) | 29940 |
| Gene symbol | DSE | Synonyms | DSE, SART2, DSEPI, SART 2, dermatan sulfate epimerase |
Background
DSE, also named as SART2 and DSEPI, is an enzyme that converts D-glucuronic acid to L-iduronic acid residues in dermatan sulphate biosynthesis. It is also identified to be a tumour-associated antigen. DSE is recognized by cytotoxic T cells (CTLs) and its enhanced expression in many cancers has been reported. DSE is a potential candidate for a tumour antigen with immunogenicity. |
