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DSE Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10452-1-AP

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Con: 20 μg/150 μl

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Tested Applications
Applications:
ELISA, IHC, IF
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10452-1-AP;human liver cancer tissue

Immunohistochemical of paraffin-embedded human liver cancer using 10452-1-AP(DSE antibody) at dilution of 1:50 (under 10x lens)

10452-1-AP;human liver cancer tissue

Immunohistochemical of paraffin-embedded human liver cancer using 10452-1-AP(DSE antibody) at dilution of 1:50 (under 40x lens)

Species specificity:
human
Positive IHC detected in:
human liver cancer tissue
Recommended dilution:
IHC : 1:20-1:200

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
DSE fusion protein ag0695
Full name:
dermatan sulfate epimerase
Calculated molecular weight:
958 aa,110 kDa
Observed molecular weight:
GenBank accession number:
BC039245
Gene ID (NCBI):
29940
Gene symbol
DSE
Synonyms
dermatan sulfate epimerase, DS epimerase, DSE, DSEPI, SART 2, SART2
Background

DSE, also named as SART2 and DSEPI, is an enzyme that converts D-glucuronic acid to L-iduronic acid residues in dermatan sulphate biosynthesis. It is also identified to be a tumour-associated antigen. DSE is recognized by cytotoxic T cells (CTLs) and its enhanced expression in many cancers has been reported. DSE is a potential candidate for a tumour antigen with immunogenicity.


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