Growth Factors

Growth factors promote cellular differentiation and proliferation. They act on target tissues and regulate processes including tissue morphogenesis, angiogenesis, cell differentiation, and neurite outgrowth.

They are essential growth-regulatory molecules for cell culture maintenance. Non-transformed cells show an absolute requirement for growth factors for maintenance in cell culture and for most cell types, more than one type of growth factor is required. Under cell culture conditions, growth factors are the most rapidly depleted media components and thus become a rate-limiting factor for further proliferation. Commonly used growth factors in tissue engineering include fibroblast growth factors (FGFs), vascular epithelial growth factors (VEGFs), and transforming growth factors-β (TGF-βs). The loss or decreased level of growth factors is common in neoplastically transformed cells and may lead to an uncontrolled growth of cancer cells.

See below for a full list of Humankine Growth Factors products:

Catalog number Product Name EC50 Purity Citations
HZ-1138 Activin A ≤5 ng/mL >95% 14
HZ-1222 beta NGF ≤4 ng/mL >95%  
HZ-1128 BMP-2 ≤60 ng/mL >95% 18
HZ-1045 BMP-4 ≤20 ng/mL >95% 33
HZ-1229 BMP-7 ≤100 ng/mL >95% 6
HZ-1168 EPO ≤2.5 ng/mL >95% 2
HZ-1285 FGF Basic TS ≤0.5 ng.mL >95% 3
HZ-1218 FGF-4 ≤1.25 ng/mL >95%  
HZ-1100 FGF-7 (KGF) ≤7.5 ng/mL >95% 1
HZ-1103 FGF-8b ≤60 ng/mL >95% 1
HZ-1151 FLT3 Ligand ≤0.8 ng/mL >95% 9
HZ-1207 G-CSF ≤0.1 ng/mL >95% 3
HZ-1311 GDNF ≤ 10 ng/mL  >95%  
HZ-1002 GM-CSF ≤2 ng/mL >95% 8
HZ-1084 HGF ≤20 ng/mL >95% 8
HZ-1007 HGH  ≤2 ng/mL >95% 1
HZ-1118 Noggin ≤25 ng/mL >95% 4
HZ-1278 Pleiotrophin-PTN   >95%  
HZ-1215 PDGF-aa ≤25 ng/mL >95%  
HZ-1308 PDGFbb 3 ng/mL >95%  
HZ-1161 pro-IGF-II ≤50 ng/mL >95%  1
HZ-1011 TGF beta 1 ≤0.5 ng/mL >95% 66
HZ-1092 TGF beta 2 ≤0.5 ng/mL >95%  4
HZ-1090 TGF beta 3 ≤0.5 ng/mL >95% 8
HZ-1204 VEGF 121 ≤15 ng/mL >95%  10
HZ-1038 VEGF 165 ≤15 ng/mL >95%  10

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