Ddit3 antibody (mAb) (Clone 9C8)
Host / Isotype
Mouse / IgG2b
Reactivity
Mouse
Applications
IP, WB
CloneNo.
9C8
Cat No : 61349,61350 61349
Synonyms
Validation Data Gallery
Product Information
Tested Applications | IP, WB |
Tested Reactivity | Mouse |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | This antibody was raised against full-length recombinant mouse Ddit3 protein. |
Full Name | Ddit3 antibody (mAb) (Clone 9C8) |
Synonyms | Ddit3, DNA-damage-inducible transcript 3, DDIT-3, CHOP10, CEBPZ, GADD153, C/EBP zeta, CHOP, CCAAT/enhancer-binding protein homologous protein, C/EBP-homologous protein 10, DNA damage-inducible transcript 3 protein, Growth arrest and DNA damage-inducible protein GADD153, C/EBP-homologous protein, CHOP-10, antibody, monoclonal, mAb, sample |
Molecular weight | 29 kDa |
GenBank accession number | NP_031863 |
RRID | AB_2614958 |
Purification Method | Protein G Chromatography |
Buffer | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
Storage | Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage. |
Background Information
Ddit3 (DNA-damage-inducible transcript 3, CHOP) is a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.