CD209 Polyclonal antibody, PBS Only

CD209 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 31621-1-PBS

Synonyms

---

Validation Data Gallery

• 

  WB analysis using 31621-1-AP (same clone as 31621-1-PBS)

  Human placenta tissue was subjected to SDS PAGE followed by western blot with 31621-1-AP (CD209 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31621-1-PBS in a different storage buffer formulation.

---

Product Information

31621-1-PBS targets CD209 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: CD209 molecule
• Calculated Molecular Weight: 404 aa, 45.7 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC110615
• Gene Symbol: CD209
• Gene ID (NCBI): 30835
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).