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  • Featured Product
  • KD/KO Validated

BMF Polyclonal antibody, PBS Only

BMF Polyclonal Antibody for IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 18298-1-PBS

Synonyms

Validation Data Gallery

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  • Immunoprecipitation (IP) experiment of HEK-293 cells using BMF Polyclonal antibody (18298-1-AP)

    IP experiment of HEK-293 using 18298-1-AP (same clone as 18298-1-PBS)

    IP result of anti-BMF (IP:18298-1-AP, 4ug; Detection:18298-1-AP 1:1000) with HEK-293 cells lysate 1800 ug. This data was developed using the same antibody clone with 18298-1-PBS in a different storage buffer formulation.

Product Information

18298-1-PBS targets BMF in IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name Bcl2 modifying factor
Calculated Molecular Weight 21 kDa
Observed Molecular Weight 24 kDa
GenBank Accession NumberBC069505
Gene Symbol BMF
Gene ID (NCBI) 90427
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

BMF belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities such as central regulators of apoptotic cell death. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. BMF is widely expressed in tissues such as pancreas, liver and kidney, and in hematopoietic tissues.