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PYROXD2 Recombinant antibody, PBS Only (Detector)

PYROXD2 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240984A12

Cat no : 83954-1-PBS

Synonyms

C10orf33, YueF, FP3420, 240984A12

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PYROXD2 Recombinant antibody (83954-1-RR)

    WB analysis using 83954-1-RR (same clone as 83954-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83954-1-RR (PYROXD2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83954-1-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP00905-1

    Cytometric bead array standard curve of MP00905-1

    Cytometric bead array standard curve of MP00905-1, C10orf33 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83954-2-PBS. Detection antibody: 83954-1-PBS. Standard: Ag14701. Range: 1.25-80 ng/mL.

  • Affinity and Kinetic Characterization of 83954-1-RR

    Affinity and Kinetic Characterization of 83954-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83954-1-RR against Human PYROXD2 were performed. The affinity constant is below 1 pM.

Product Information

83954-1-PBS targets PYROXD2 as part of a matched antibody pair:

MP00905-1: 83954-2-PBS capture and 83954-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen PYROXD2 fusion protein Ag14701
Full Name chromosome 10 open reading frame 33
Calculated Molecular Weight 581 aa, 63 kDa
Observed Molecular Weight63 kDa
GenBank Accession NumberBC006131
Gene Symbol PYROXD2
Gene ID (NCBI) 84795
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Pyridine Nucleotide-Disulfide Oxidoreductase Domain 2 (PYROXD2, previously called YueF, C10orf33) is a mitochondrial inner membrane/matrix-residing protein and is reported to regulate mitochondrial function. PYROXD2 is highly expressed in the cytoplasm of normal cells and tissues but is expressed at lower levels in corresponding cancer cells, including liver, lung and renal cell carcinoma and bladder cancer cells (PMID: 29048625, PMID: 35606887).